Special Application Systems with Phospholipids


A fast-dispersible hydrogenated phospholipid formulation increasing the dissolution of poorly soluble actives in water


Hydrogenated phospholipids (PL) from lecithin are natu- ral products useful for pharmaceutical and cosmetic ap- plications. Due to their higher TC than unsaturated phospholipids, hydration of the phospholipids to form liposomal dispersions requires higher temperatures. SOLUTHIN® MD H is a dry mixture of maltodextrin with pre-formed liposomes made from hydrogenated PL from non-GMO soybean with not less than 18% hydrogenated soybean phosphatidylcholine (HSPC). It was shown to be readily dispersible in water at 25 °C, forming stable dispersions and capable of solubilizing a lipophilic compound in water as well as in a medium simulating the fed state gastrointestinal tract (GI).


More up from page 14 in the Newsletter - see download

Newsletter Volume 11 - Phospholipid Research Center Heidelberg
PRC_Newsletter Vol11-1-2017.pdf
Adobe Acrobat Document 2.1 MB