Photo of tablets with tailored film coating
20. April 2018
Do you need a tablet film coating with natural colors and TiO2-free? Pharmaexcipients.com offers the access to the film coating experts from BIOGRUND US, Sterling. VA. They put together a tailored ready to use coating based on your application in a fast and simple way. Just fill in the questionnaire and you will get a free sample.

Tailored Film Coating
20. April 2018
Are you looking for a tailored film coating for your product? pharmaexcipients offers the access to film coating experts to put together a tailored coating based on your application and needs in a fast and simple way. Just fill in the questionnaire

20. April 2018
Silica-based nanoparticles are used as excipients in pharmaceutical technology. Recently, mesoporous silica nanoparticles have emerged as drug delivery systems. Their porous structure enables the high drug-loading of drugs with poor water solubility. The silica matrix protects entrapped drugs against enzymatic degradation. Furthermore, the premature release of drugs is hindered by pore-gating strategies. Adding a targeting ligand to the silica-based nanoparticles directs them to diseased cells...

19. April 2018
Cell-free permeation systems are gaining interest in drug discovery and development as tools to obtain a reliable prediction of passive intestinal absorption without the disadvantages associated with cell- or tissue-based permeability profiling. Depending on the composition of the barrier, cell-free permeation systems are classified into two classes including (i) biomimetic barriers which are constructed from (phospho)lipids and (ii) non-biomimetic barriers containing dialysis membranes. This...

19. April 2018
Excipients are materials added along with therapeutic agents; and incompatibility between excipients and therapeutic agents affect the final outcome of the product. Aspirin is an ester and is prone to hydrolysis. This study focus on the effect of magnesium stearate as an excipient on stability of aspirin in granules. For that an accelerated degradation study was done on aspirin-magnesium stearate containing granules. For that, aspirin containing granules were sequentially mixed with increasing...

19. April 2018
The Complete List and Analysis of the 10 Best Pharmaceutical Companies in 2018. 7 criteria have been considered including revenue, growth, R&D investments, and others. The global pharmaceutical market was estimated at USD 1.11 trillion in 2017 and projected to reach USD 1.43 trillion by 2020. In 2017, North America, Asia Pacific and Western Europe pharmaceutical market approximately accounted for 37%, 22% and 20% global market share respectively. In 2017, top-10 global pharmaceutical...

Preparation Method and Amorphous Systems
18. April 2018
A video explanation by Dr. Thomas Rades featured by Pharmatech and BASF. The preparation method is crucial in solid amorphous systems. “It really matters how we prepare them – depending on the method we are using, we are landing somewhere else on the energy landscape.” In this feature with Pharmtech, Dr. Thomas Rades from University of Copenhagen explains different preparation methods and their consequences for the stability of amorphous systems.

18. April 2018
Certificates of analysis (CoAs) are a tangible, and important, manifestation of a manufacturer’s relationship with its suppliers of APIs, excipients, and the other materials used to make drug products. Provided by suppliers to customers as a matter of course, these documents operate at the point where materials, laboratory control systems, and manufacturing intersect.
18. April 2018
A 3D-Bioplotter® was employed to 3D print (3DP) a humic acid-polyquaternium 10 (HA-PQ10) controlled release fixed dose combination (FDC) tablet comprising of the anti-HIV-1 drugs, efavirenz (EFV), tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC). Methods Chemical interactions, surface morphology and mechanical strength of the FDC were ascertained. In vitro drug release studies were conducted in biorelevant media followed by in vivo study in the large white pigs, in comparison with a...

18. April 2018
Many people cannot swallow whole tablets and capsules. The cause ranges from difficulties overriding the natural instinct to chew solids/foodstuff before swallowing, to a complex disorder of swallowing function affecting the ability to manage all food and fluid intake. Older people can experience swallowing difficulties because of co-morbidities, age-related physiological changes, and polypharmacy. To make medicines easier to swallow, many people will modify the medication dosage form e.g....

Show more