What does the future hold for pharmaceutical excipients?

Many of the excipients we use today have been around for more than fifty years. In many cases, the specifications for those excipients have not changed much over the years, either. During that time, we have not really thought about what happens when our existing excipients, and/or their specifications, are no longer able to provide us with the necessary performance to allow effective medicines to be

formulated, developed and manufactured on a routine basis. Things are changing!

 

We have moved into a new era. With the advent of combinatorial chemistry,

high-throughput screening, recombinant technologies and better understanding of

proteins, drug-receptor interactions, monoclonal antibodies, and the like, today we

have very sophisticated tools which help us to discover very effective drugs we could hardly imagine fifty years ago. However, innovation in excipients has not kept pace with the advances in drug discovery.

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What does the future hold for pharmaceutical excipients?
R.Christian Moreton - FinnBrit Consulting
This Journal is © IPEC-Americas Inc June 2017 J. Excipients and Food Chem. 8 (2) 2017
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