Solution through compounding: Flavouring for children: Part 2

Abstract: This article is the second part of a series on flavouring for children's formulations. Omeprazole has been chosen as an example of an active pharmaceutical ingredient (API) that is not commercially available as an oral liquid, and is also unstable and sensitive to degradation under certain conditions. This provides a challenge to pharmacists to formulate a stable mixture for oral delivery. The stability of omeprazole and lack of an appropriate commercially available product for children were detailed in Part 1 of this series. This article focuses on the important organoleptic properties (aspects experienced via the senses including taste, sight, smell, and touch), where the addition of flavours and sometimes sweetening agents are required to produce an oral liquid which is palatable for children. (Note: some of the information presented in this article has been repeated from the Part 1 article published in the Australian Pharmacist November 2016 issue.)