Have existing pharmaceutical excipients failed to enable oral/nasal protein delivery?
ABSTRACT
It seems evident that the ill-defined weltanschauung of the past decade of enabling oral, un-truncated permeability-dependent protein delivery carte-blanche, using existing excipients has produced sparse results. Existing excipients are better utilized for exploiting niches which do not require either permeation or a permeation enhancement incongruent and/or is disproportionate to the existing excipient molecules’ ability.
March 2017 J. Excipients and Food Chem. 8 (1) 2017