Phospholipids: Unique carriers for drug delivery systems


The aim of this review is to draw attention on potential applications of phospholipids in drug delivery system through different sources, structure, properties and as carrier. Phospholipids have the exceptional biocompatibility and remarkable amphiphilicity characteristics that make phospholipids the major and suitable agent or excipient for the formulation and to achieve better therapeutic applications in drug delivery system. The applications of phospholipids in the drug delivery systems are enhancement of bioavailability of drugs with low aqueous solubility or low membrane penetration, an improvement or alteration the uptake and release profile of drugs, protection of sensitive active agents from degradation in the GIT tract, reduced the side effects and masking of bitter taste of drugs. These properties offer various possibilities in formulation and potential applications.