Medical Marijuana: Improving stability with novel delivery methods

ABSTRACT: Medical Marijuana products can be one of most promising therapeutics in the near future. However, its pharmaceutical use poses many formulation challenges: absortion, dosage variability, strain differences, extraction methods makes it potentially unpredictable. The purest and more effective forms of THC (99.9%) are highly unstable due to oxidation on room air, AXIM Biotechnologies patented a micro-encapsulation technology using gum base that preserves its integrity while ensuring drug delivery in 20 minutes or less (compared to previous efforts where chewing gum retained up to 50% of the APIs since cannabinoids are highly hydrophobic and lipophilic, they were adhering too much to the gum base and not being released properly).