Superdisintegrants: introduction to chemistry and Performance - DFE Pharma


The superdisintegrants Primojel® (sodium starch glycolate) and Primellose® (croscarmellose sodium) are cross-linked and substituted polymers of glucose. The degree of cross-linking and substitution are

important factors in determining the effectiveness of these materials as superdisintegrants. In the case of Primojel®, the selection of the type of starch is also a key factor, and in the case of Primellose®, particle size is important. This introduction to the chemistry and performance of superdisintegrants describes how the synthetic processes have been optimised to ensure peak performance of these two materials.

Superdisintegrants Introduction chemistr
Adobe Acrobat Document 774.2 KB