Abstract

Microcrystalline cellulose (MCC) HiCelTM is native from cellulose, which is manufactured from wood pulp. Microcrystalline cellulose is made by hydrolysis reaction at temperature and pressure in presence of catalyst, which acts as reaction process increment. It is neutralized after completion of hydrolysis and intended to be used as to make microcrystalline cellulose powder. HiCelTM MCC is white crystalline, free flowing powder and medium in particles size. MCC is free flowing with having physical & chemical properties as per limit and widely used as a pharmaceuticals aid for direct compression & wet granulation. MCC is employed for the production of solid dosage form due to its good compressibility, compatibility, and loading capacity of drugs. HiCelTM is very essential for direct compression because of its all parameter support to direct compression.