A robust excipient, STARLAC® could be considered as perfect filler binder for direct compression applications, combining fast tablet disintegration with easy tableting.

The co-processed starch-lactose compound STARLAC® is an excipient perfectly adapted to direct compression by combining superior tableting properties with high disintegration power. It is obtained by co-spray drying of 85% monohydrate lactose and 15% of white maize starch. STARLAC® has been designed to reach in all conditions optimal tablet disintegration.

Nevertheless several authors describe important improvements of tableting parameters, such as reduced ejection forces, compared to physical blends of lactose and starch.

The aim of this work was to check the robustness of STARLAC® when used as a general DC excipient by testing it on a compression simulator STYLCAM 200 R and varying crucial tableting parameters.

Scientific Paper