Drop forming as a basis for a scaling up of the in situ coating process
Cutting the costs of tablet manufacture is one of the many advantages melt crystallization offers compared to conventional tableting procedure as a technology for producing pharmaceutical coated tablets. Other advantages include the lower number of steps needed for production, which increases productivity; the lower energy and workforce requirements; and the decreased need for stricter post-production quality control measures while maintaining quality. The scientific term for maintaining quality is ensuring the reproducibility of experimental results. The main focus of this study is to scale up the drop-forming process of coating, in this case of ibuprofen tablets using Lutrol.