Itraconazole (ITZ) is a broad spectrum triazole antifungal drug and commercially available as oral forms. However, effective topical forms are interesting to avoid systemic adverse effects, to directly deliver antifungal drugs to the target sites and to enhance patient compliance [1]. Microemulsion-based hydrogel (MBH), semisolid form of microemulsion (ME), is one of novel formulations practically used as topical drug carriers [2]. This study aimed to develop formulations of ITZ-loaded MBHs having advantageous properties and high stability.

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