Solid Self-emulsified Nanostructures of Lercanidipine Hydrochloride: A Potential Approach to Improve the Fraction of the Dose Absorbed
The aim of current research was to develop and characterize solid self-emulsified nanostructures (S-SEN) loaded with a BCS class II drug, Lercanidipine hydrochloride (LCH). The liquid self-emulsified nanostructures (L-SEN) were prepared using rice bran oil and glyceryl monooleate (GMO) as oil phase and Tween 80 and propionic acid as surfactant and co-surfactant respectively.