Prediction of Powder Flow Performance using a Multi-component Granular Bond Number

  • The flow function coefficients (ffc) of pharmaceutical materials were evaluated.

  • Dry coating was also used to modify the surface properties of the materials.

  • The ffc was found to correlate well with the granular Bond number.

  • A Granular Bond Number for multi-component mixtures (i.e. blends) was formulated.

  • The multi-component Bond number predicted the ffc of 2, 3, and 5 component blends.

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