Novel doped calcium phosphate-PMMA bone cement composites as levofloxacin delivery systems – Abstract
Highlights
•Novel BC composites with improved mechanical integrity.
•Sustained in vitro release of the antibiotic (levofloxacin) from the BC composites over an 8-week period.
•Levofloxacin retained the antimicrobial activity against Staphylococcus aureus and Staphylococcus
epidermidis over an 8-week in vitro release period.