Highlights

• Solubility and dissolution of Albendazole was greatly enhanced.

• Benzoic acid generated hydrogen bonding with drug and changed crystal habit.

• Flow property and compressibility was significantly improved.

• Bioavailability of drug was enhanced by many folds compared to pure drug.

 

http://www.sciencedirect.com/science/article/pii/S0921883115000990

Mihir K. Raval, , Pooja D. Vaghela , Ashish N. Vachhani , Navin R. Sheth 

Department of Pharmaceutical Sciences, Saurashtra University, Rajkot 360 005, Gujarat, India

Received 14 December 2014, Revised 3 May 2015, Accepted 13 May 2015, Available online 23 May 2015