Formulation and evaluation of biodegradable nanoparticles for the oral delivery of fenretinide.
Fenretinide is an anticancer drug with low water solubility and poor bioavailability. The goal of this study was to develop biodegradable polymeric nanoparticles of fenretinide with the intent of increasing its apparent aqueous solubility and intestinal permeability…
http://www.ncbi.nlm.nih.gov/pubmed/25933716
Eur J Pharm Sci. 2015 Apr 28. pii: S0928-0987(15)00179-7. doi: 10.1016/j.ejps.2015.04.024.